![]() On the other hand, mupirocin (generic name for Bactroban) is another type of topical antibiotic but it's typically used for treating minor skin infections such as impetigo or folliculitis. The drug has a broad influence on many types of bacteria, including some strains resistant to other antibiotics. It's commonly prescribed for burn victims or those with significant skin injuries. First approved by the FDA in 1973, Silvadene works by inhibiting the growth of bacteria that could infect an open wound. Silver sulfadiazine (the generic name for Silvadene) is a topical cream primarily used to prevent and treat infections in severe burns. On the other hand, Bactroban (mupirocin) inhibits bacterial protein synthesis by binding to an enzyme known as isoleucyl-tRNA synthetase, preventing bacteria from growing and multiplying – it's primarily used for minor skin infections like impetigo. ![]() Silvadene is a sulfa drug that directly kills bacteria while forming a protective barrier over the affected area, commonly used for treating serious burns. Each has a different mechanism of action but both serve to fight off bacterial invaders on the skin surface. Silvadene and Bactroban are two such drugs that are often prescribed for these conditions. For patients with skin infections or burns, certain topical antibiotics that prevent the growth of bacteria on the skin can help in managing symptoms and promoting healing.
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